A 30 year old man, has symptoms as: profound loss of appetite, aversion to smoking among smokers, dark urine, yellowing of the eyes and skin and abdominal discomfort. The liver function tests showed ALT: 2500 U/L (Normal range: 10-40 U/L), AST: 1400 U/L (Normal range: 10-40 U/L), GGT: 45 U/L (Normal range: 7-32 U/L),Total Bil: 120 umol/L (Normal range: 0-20 umol /L), Direct Bil: 80 umol/L (Normal range: 0-6.8 umol /L). What's your gross diagnosis? ( )