Alkalization of urine by giving bicarbonate is used to treat patients presenting with pheobaarbital(weak acid) overdose. Which of the following best describes the rationale for alkalization of urine in this setting?
A.
To reduce tubular reabsorption of phenobarbital.
B.
To reduce ionization of phenobarbital.
C.
To increase glomerular filtration of phenobarbital.
D.
To increase proximal tubular secretion
E.
To increase tubular reabsorption of phenobarbital.