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【多选题】
DNA replication needs（ ）
A.
helicase
B.
primase
C.
topoisomerase
D.
DNA ligase
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举一反三
【单选题】Which statement is true about oncogenes?（ ）
A.
Oncogenes are only present in cancer cells
B.
Hypermethylation happens in their promoter region
C.
Their products inhibit cell proliferation
D.
They are usually activated in cancer development
【单选题】The specific sequence on the N terminus of secretory protein is called （ ）
A.
secretory peptide
B.
signal sequence
C.
signal petidase
D.
signal peptide
【单选题】The most efficient step of gene expression regulation is （ ）
A.
transcription initiation
B.
translation initiation
C.
activation of chromosomes
D.
transcription termination
【单选题】The basic steps of PCR reaction are: （ ）
A.
denaturation, annealing, extension
B.
annealing, extension, denaturation
C.
denaturation, extension, annealing
D.
annealing, denaturation, extension
【单选题】Which of the following statements is not true concerning Type II restriction endonucleases?（ ）
A.
Sticky ends or blunt ends are produced after digestion
B.
They can cleave single DNA
C.
Cut DNA into fragments at recognition site
D.
Recognize palindrome sequence
【多选题】The blood of kidney is characterized by（ ）
A.
Large blood flow, mainly supplying the renal cortex
B.
Renal blood flow can be self-regulated
C.
Go through the capillary network twice
D.
Hypotension in capillaries around renal tubules
E.
High blood pressure in glomerular capillaries
【多选题】The role of angiotensin II is（ ）
A.
To induce the release of norepinephrine from sympathetic nerve endings
B.
To constrict the volume vessels
C.
To promote aldosterone release
D.
To contract arterioles throughout the body
E.
To increase the tension of the sympathetic vasoconstrictor center
【多选题】Which is correct in the following statements about the central chemoreceptor （ ）.
A.
It locates at the superficial part of the ventrally lateral medulla oblongata
B.
It can feel hypoxia stimulation
C.
It has lower sensitivity to CO2 than peripheral chemoreceptors
D.
H+ in blood easily passes through the blood-brain barrier and rapidly stimulates central chemoreceptors
E.
It has higher sensitivity to H+ than peripheral chemoreceptors
【多选题】What are the differences of eukaryotic DNA replication from prokaryotes? （ ）
A.
the replication origin of eukaryotes is shorter than that in prokaryotes
B.
telomere and telomerase aid termination of eukaryotes
C.
eukaryotic DNA contains multiple origins
D.
eukaryotic DNA is replicated in S phase of cell cycle